CHARM Therapeutics logo — Protein-ligand intelligence to deliver next generation small...

CHARM Therapeutics

Protein-ligand intelligence to deliver next generation small molecule therapeutics

Founded 2021 United Kingdom London, United Kingdom 32 employees Series B Total: $162.60M AI, Biotechnology +1

General Information

Company Name CHARM Therapeutics
Founded Year 2021
Location United Kingdom London, United Kingdom +2
Employees 32
Industries AI, Biotechnology, Life Sciences
Funding Stage Series B
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About CHARM Therapeutics

CHARM Therapeutics, founded in 2021 and headquartered in the United Kingdom, is at the forefront of innovation in the AI, Biotechnology, and Life Sciences industries. Guided by the slogan, "Protein-ligand intelligence to deliver next generation small molecule therapeutics," the company is pioneering the development of novel treatments for acute myeloid leukemia (AML).

Their leading program focuses on a groundbreaking, next-generation menin inhibitor. Unlike existing solutions that struggle with resistance mutations, CHARM's candidate maintains potency against all known clinical resistance mutations, offering a potential breakthrough for achieving long-lasting treatment responses in AML patients.

Recently, CHARM Therapeutics secured an $80.00M Series B investment on 01 September 2025, attracting a strong consortium of investors, including F-Prime Capital, Khosla Ventures, Nvidia, OrbiMed, NEA, and SR One. This robust funding highlights the confidence and strategic interest from prominent venture capital in the company's compelling vision and technological advancement.

Taxonomy: protein-ligand intelligence, small molecule therapeutics, menin inhibitor, acute myeloid leukemia treatment, resistance mutation management, potency retention, 3D deep learning, drug discovery technologies, undruggable targets, transformational medicines, next-generation therapeutics, clinical resistance overcoming

Services & Products

Development of best-in-class menin inhibitors
Advancing drug candidates to clinical trials
Research on protein-ligand interactions

Target Customers

Patients with Acute Myeloid Leukemia (AML) Healthcare Providers specializing in Oncology Research Institutions

Funding Rounds & Investors (4)

View All
Funding Stage Amount Investors Lead Investors Date
Series B •••••• 6
Investor Investor Investor Investor Investor Investor
01 Sep 2025
Early VC •••••• 1
Investor
01 Apr 2023
Series A •••••• 6
Investor Investor Investor Investor Investor
•••• ••••
01 Jun 2022
Early VC •••••• - 01 Oct 2021

CHARM Therapeutics Alternatives & Competitors

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CHARM Therapeutics vs
Kura Oncology, Inc.
Kura Oncology, Inc. United States

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CHARM Therapeutics vs

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CHARM Therapeutics vs

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FAQ About CHARM Therapeutics

Protein-ligand intelligence to deliver next generation small molecule therapeutics
CHARM Therapeutics was founded in 2021.
CHARM Therapeutics is headquartered in London, United Kingdom.
CHARM Therapeutics operates in the following industries: AI, Biotechnology, Life Sciences.
CHARM Therapeutics has approximately 32 employees.
CHARM Therapeutics has completed 4 funding rounds, raising a total of $162.60M. The latest funding stage is Series B.
CHARM Therapeutics offers: Development of best-in-class menin inhibitors, Advancing drug candidates to clinical trials, Research on protein-ligand interactions.
Top alternatives and competitors to CHARM Therapeutics include Kura Oncology, Inc., ORIC Pharmaceuticals Inc., Kurome Therapeutics, Inc., Bright Angel Therapeutics, TOLREMO therapeutics. These companies operate in related industries and serve comparable markets. You can compare them side by side on Bounce Watch.
CHARM Therapeutics and Kura Oncology, Inc. are both companies in similar industries. Compare their funding, team size, growth signals, and market position on Bounce Watch to see which one fits your needs.

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