Fulcrum Therapeutics logo — company profile

Fulcrum Therapeutics

Founded 2016 United States Cambridge, United States 74 employees Post-IPO Equity Total: $603.30M Biotechnology, Health Care +1

General Information

Company Name Fulcrum Therapeutics
Founded Year 2016
Location United States Cambridge, United States
Employees 74
Industries Biotechnology, Health Care, Health and Wellness
Funding Stage Post-IPO Equity
Business Model B2B2C, B2B
Revenue Model Licensing, Product Sales, Performance Based
Social

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About Fulcrum Therapeutics

Fulcrum Therapeutics is a clinical-stage biopharmaceutical company established in 2016 and based in the United States. It aims to enhance the lives of patients who suffer from genetically defined diseases, especially those in urgent need, with a primary focus on rare diseases.

Positioned at the intersection of biotechnology and health care, Fulcrum Therapeutics is making strides in the health and wellness industry by leveraging cutting-edge research to address significant gaps in medical treatments. The company's focus on untreated or inadequately treated conditions has the potential to disrupt traditional therapeutic approaches.

In January 2023, Fulcrum Therapeutics secured a $125.00M post-IPO equity investment. This significant capital injection underpins its mission to advance its clinical programs and broaden its research scope.

The company's continuous commitment to innovation and its robust early-stage performance present a compelling opportunity for investors looking to support transformative solutions in the healthcare sector.

Business keywords: Biopharmaceutical, Rare Diseases, Genetic Diseases, Clinical Stage, Gene Expression Modulation, Drug Development, Neuromuscular Diseases, Cardiovascular Diseases, Losmapimod, Cambridge, Massachusetts, Proprietary Product Engine, Clinical Trials, Muscle-Wasting Disorders, Gene Regulation, FSHD

Services & Products

Modulating gene expression
Clinical trial development
Research and development in genetically defined diseases
Therapeutic innovation

Target Customers

Patients with sickle cell disease Patients with beta-thalassemia Healthcare providers Medical researchers Investors in biotech and pharmaceuticals

Funding Rounds & Investors (8)

View All
Funding Stage Amount Investors Lead Investors Date
Post IPO Equity $125.00M -
17 Jan 2023
Post IPO Equity $75.00M -
15 Aug 2022
Post IPO Equity $144.20M -
10 Aug 2021
Post IPO Equity $50.60M -
19 Jan 2021
Post IPO Equity $68.50M 8
Casdin Capital, Boxer Capital +6
09 Jun 2020
Series B $80.00M 8
Casdin Capital, 6 Dimensions Capital +6
05 Sep 2018
Series A $5.00M 1
GV
10 May 2017
Series A $55.00M 1
Third Rock Ventures
19 Jul 2016

Fulcrum Therapeutics Alternatives & Competitors

View All Alternatives
Fulcrum Therapeutics vs
Forma Therapeutics
Forma Therapeutics United States

Dedicated to transforming the lives of patients with rare hematologic diseases and cancers.

Series D
159 employees
Biotechnology, Health Care
Fulcrum Therapeutics vs
AGTC
AGTC United States

Visionary science for life-changing cures.

Post-IPO Equity
117 employees
Biotechnology, Health Care
Fulcrum Therapeutics vs
Avalo Therapeutics
Avalo Therapeutics United States

Innovation driven by compassion.

Post-IPO Equity
48 employees
Biotechnology, Health and Wellness

FAQ About Fulcrum Therapeutics

We are a clinical-stage biopharmaceutical company focused on improving the lives of patients with genetically defined diseases in areas of high unmet medical need, with an initial focus on rare diseases. Community Guidelines: https://bit.ly/3t2xeR9
Fulcrum Therapeutics was founded in 2016.
Fulcrum Therapeutics is headquartered in Cambridge, United States.
Fulcrum Therapeutics operates in Biotechnology, Health Care and Health and Wellness. Its work centres on Biopharmaceutical, Rare Diseases, Genetic Diseases and Clinical Stage. Its customers include Patients with sickle cell disease, Patients with beta-thalassemia and Healthcare providers.
Fulcrum Therapeutics has a B2B2C and B2B business model. Its revenue comes from Licensing, Product Sales and Performance Based.
Fulcrum Therapeutics has approximately 74 employees.
Fulcrum Therapeutics has completed 8 funding rounds, raising a total of $603.30M. The latest funding stage is Post-IPO Equity.
Fulcrum Therapeutics offers: Modulating gene expression, Clinical trial development, Research and development in genetically defined diseases, Therapeutic innovation.
Top alternatives and competitors to Fulcrum Therapeutics include Forma Therapeutics, AGTC, Avalo Therapeutics, Therachon, GENFIT. These companies operate in related industries and serve comparable markets. You can compare them side by side on Bounce Watch.
Fulcrum Therapeutics and Forma Therapeutics are both companies in similar industries. Compare their funding, team size, growth signals, and market position on Bounce Watch to see which one fits your needs.

Source: BounceWatch company record for Fulcrum Therapeutics, https://bouncewatch.com/company/fulcrum-therapeutics, updated 5 April 2026. When citing, please name BounceWatch and link this page.

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