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Plexium logo — Pushing the Boundaries of Targeted Protein Degradation to Im...

Plexium

Pushing the Boundaries of Targeted Protein Degradation to Improve Lives

Founded 2018 United States San Diego, United States 35 employees Series B Total: $165.00M Biotechnology, Health Care +2

General Information

Company Name Plexium
Founded Year 2018
Location United States San Diego, United States
Employees 35
Industries Biotechnology, Health Care, Health and Wellness +1
Funding Stage Series B
Business Model B2B, Platform
Revenue Model Licensing, Performance Based, Product Sales
Social

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About Plexium

Plexium, founded in 2018, is a pioneering biotechnology company based in the United States. The company is redefining the landscape of targeted protein degradation (TPD) with the ambitious mission of "Pushing the Boundaries of Targeted Protein Degradation to Improve Lives."

Plexium's innovation primarily revolves around its DELTA Discovery™ platform, which includes a unique ultra-high throughput (uHTS) cell-based screening capability. This technology positions Plexium as a leader with the potential to deliver first-in-class and best-in-class treatments, addressing high unmet medical needs in the biotechnology, health care, health and wellness, and pharmaceutical sectors.

Having secured a substantial $102.00M Series B investment on 23 February 2022, Plexium is backed by an impressive roster of investors, including Lux Capital, Neotribe Ventures, RA Capital Management, Pivotal bioVenture Partners, and SoftBank Vision Fund, underscoring strong confidence in its innovative approach and market potential.

Business keywords: Targeted Protein Degradation, Next-Generation Therapeutics, Monovalent Direct Degraders, Molecular Glues, Small Molecule Drugs, High Unmet Medical Needs, DELTA Discovery Platform, Ultra-High Throughput Screening, Cancer Therapies, Clinical-Stage Degraders, Druggable Target Expansion, Protein Degraders, PROTAC Alternatives, Therapeutic Innovation

Services & Products

Rational design and discovery of protein degraders
Development of targeted protein degradation therapeutics
Clinical trials

Target Customers

Patients with high unmet medical needs Healthcare institutions and systems Pharmaceutical partners

Funding Rounds & Investors (6)

View All
Funding Stage Amount Investors Lead Investors Date
Series B $102.00M 10
Lux Capital Neotribe Ventures RA Capital Management
Lux Capital, Neotribe Ventures +8
23 Feb 2022
Series A $35.00M 4
Lux Capital Pivotal bioVenture Partners The Column Group
Lux Capital, Pivotal bioVenture Partners +2
19 Jan 2021
Series A $28.00M 3
CRV Neotribe Ventures The Column Group
CRV, Neotribe Ventures +1
17 Oct 2019
Series A Undisclosed 1
DCVC Bio
25 Apr 2019
Seed Round Undisclosed 1
DCVC Bio
01 Oct 2018
Seed Round Undisclosed 1
CRV
CRV
01 Feb 2018

Plexium Alternatives & Competitors

View All Alternatives
Plexium vs
Biotheryx, Inc.
Biotheryx, Inc. United States

Degrading proteins. Saving lives. Building the leader in next-generation targeted protein degradatio...

Series E
25 employees
Biotechnology, Health Care
Compare Plexium vs Biotheryx, Inc.
Plexium vs
Degron Therapeutics
Degron Therapeutics United States

Aims to become a global leader in the discovery and development of molecular glue degraders

Series A
25 employees
Biotechnology, Health Care
Compare Plexium vs Degron Therapeutics
Plexium vs
Differentiated Therapeutics Inc
Differentiated Therapeutics Inc United States

What if you could predict molecules to make the cause of disease disappear?

Seed
3 employees
Biotechnology, Health and Wellness
Compare Plexium vs Differentiated Therapeutics Inc
Also compare with: Plexium vs Avilar Therapeutics Avilar Therapeutics View all alternatives

FAQ About Plexium

Pushing the Boundaries of Targeted Protein Degradation to Improve Lives
Plexium was founded in 2018.
Plexium is headquartered in San Diego, United States.
Plexium operates in Biotechnology, Health Care, Health and Wellness and Pharmaceutical. Its work centres on Targeted Protein Degradation, Next-Generation Therapeutics, Monovalent Direct Degraders and Molecular Glues. Its customers include Patients with high unmet medical needs, Healthcare institutions and systems and Pharmaceutical partners.
Plexium has a B2B and Platform business model. Its revenue comes from Licensing, Performance Based and Product Sales.
Plexium has approximately 35 employees.
Plexium has completed 6 funding rounds, raising a total of $165.00M. The latest funding stage is Series B.
Plexium offers: Rational design and discovery of protein degraders, Development of targeted protein degradation therapeutics, Clinical trials.
Top alternatives and competitors to Plexium include Biotheryx, Inc., Degron Therapeutics, Differentiated Therapeutics Inc, Monte Rosa Therapeutics, DELIVER Therapeutics, Inc.. These companies operate in related industries and serve comparable markets. You can compare them side by side on Bounce Watch.
Plexium and Biotheryx, Inc. are both companies in similar industries. Compare their funding, team size, growth signals, and market position on Bounce Watch to see which one fits your needs.

Source: BounceWatch company record for Plexium, https://bouncewatch.com/company/plexium, updated 29 June 2026. When citing, please name BounceWatch and link this page.

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