89bio is a clinical-stage biopharmaceutical company with a focus on developing and commercializing innovative therapies for the treatment of liver and cardio-metabolic diseases. Their lead product candidate, BIO89-100, is an engineered glycoPEGylated analog of FGF21 designed for the treatment of nonalcoholic steatohepatitis (NASH) and severe hypertriglyceridemia (SHTG). The company's recent Phase 1b/2a data showed favorable safety and tolerability profiles and significant reductions in liver fat and key lipid markers in patients with NASH. BIO89-100 is currently in a Phase 2 trial for the treatment of SHTG. Founded in 2018 and headquartered in San Francisco with operations in Herzliya, Israel, 89bio upholds a strong set of values, including prioritizing patient needs, integrity, authenticity, teamwork, entrepreneurship, and scientific rationality.
The company's last investment of $150.00M in post-IPO equity occurred on 06 December 2023.