insitro logo — insitro is the physical AI company built on causal biology....

insitro

insitro is the physical AI company built on causal biology. ┈➤ Find us on Substack: http://DeepPhenotype.substack.com

Founded 2018 United States South San Francisco, United States 255 employees Series C Total: $643.00M Biotechnology

General Information

Company Name insitro
Founded Year 2018
Location United States South San Francisco, United States
Employees 255
Industries Biotechnology
Funding Stage Series C
Business Model B2B, Platform, SaaS
Revenue Model Licensing, Service Fee, Subscription
Offices as of Aug 2026
South San Francisco, United States
Social

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Recorded by Bounce Watch from public sources. Every entry below carries the date we observed it, and when we have not looked recently the page says so rather than leaving silence to imply nothing happened.

New Partnership Oct 06, 2026

insitro announced a partnership with Eli Lilly and Co., enabling biotech companies in the Lilly TuneLab™ network to deploy advanced machine learning models built by the two companies to predict sma…

Event Participation Oct 05, 2026

insitro will be participating in three panel discussions at @SFTechWeek 2026, with one panel, 'Molecules, Models & Agents', scheduled for October 5, 2026.

AI Insight

Bounce Watch AI
1 month ago

insitro is strategically transitioning towards becoming a clinical-stage company, evidenced by multiple programs advancing to First-in-Human trials and the active recruitment for a VP of Regulatory Affairs. This significant pivot is further bolstered by the recent appointment of a Chief Medical Officer, underscoring an accelerated push into clinical development and regulatory preparedness for their therapeutic pipeline.

Signal Types
Milestone Hiring
Strategic Labels
Clinical Stage Transition Regulatory Preparedness Executive Strengthening
Next Move: Clinical Trials
·
Impact: 8/10
·
Ideal For: Late-Stage Biotech Investors

About insitro

insitro, founded in 2018 and headquartered in the United States, is making strides in the Biotechnology industry with its novel approach to blending physical AI and causal biology. Under the leadership of AI pioneer Daphne Koller, the company is constructing the Virtual Human™, a sophisticated AI engine that deciphers human biology to unveil disease mechanisms and treatment pathways.

With its innovative TherML™ AI platform, insitro aims to propel the development of therapeutics, particularly in neuroscience and metabolic disorders. This cutting-edge strategy has attracted substantial investor interest, evidenced by a robust $400.00M in Series C funding on 01 March 2021.

Notable investors include CPP Investments, Two Sigma Ventures, Arch Venture Partners, and Andreessen Horowitz/a16z, among others. This backing underscores a shared belief in insitro's potential to redefine medicine through scalable biological insights and enhanced drug discovery.

Business keywords: Causal Biology, AI in Drug Development, TherML AI Platform, Neuroscience Therapeutics, Metabolic Disease Treatment, Genetic Drivers Identification, Predictive Biology Models, Machine Learning in Medicine, Bioinformatics, Integrated Multi-modal Data, Virtual Human Technology, Precision Medicine, Biomedical Data Integration

Services & Products

Causal AI Systems Development
Therapeutics Design through AI
Disease Target Identification
Clinical and Cellular Data Integration

Target Customers

Pharmaceutical Companies Biotech Researchers Healthcare Providers Drug Development Firms

Funding Rounds & Investors (4)

View All
Funding Stage Amount Investors Lead Investors Date
Series C $400.00M 13
CPP Investments, Two Sigma Ventures +11
01 Mar 2021
Series B $143.00M 12
CPP Investments, Two Sigma Ventures +10
01 May 2020
Series A $100.00M 8
Two Sigma Ventures, Arch Venture Partners +6
01 Apr 2019
Series A Undisclosed -
01 May 2018

insitro Alternatives & Competitors

View All Alternatives
insitro vs
Cellarity
Cellarity United States

Rewriting the rules of drug creation

Series C
76 employees
Biotechnology, Life Sciences
insitro vs
DeepLife
DeepLife France

AI for digital twin of cells

Series A
31 employees
AI, Biotechnology
insitro vs
Manifold Bio
Manifold Bio United States

Organism-scale intelligence, designed in vivo

Series A
69 employees
Biotechnology, Health Care

FAQ About insitro

insitro is the physical AI company built on causal biology. ┈➤ Find us on Substack: http://DeepPhenotype.substack.com
insitro was founded in 2018.
insitro is headquartered in South San Francisco, United States.
insitro operates in Biotechnology. Its work centres on Causal Biology, AI in Drug Development, TherML AI Platform and Neuroscience Therapeutics. Its customers include Pharmaceutical Companies, Biotech Researchers and Healthcare Providers.
insitro has a B2B, Platform and SaaS business model. Its revenue comes from Licensing, Service Fee and Subscription.
insitro has approximately 255 employees.
insitro has completed 4 funding rounds, raising a total of $643.00M. The latest funding stage is Series C.
insitro offers: Causal AI Systems Development, Therapeutics Design through AI, Disease Target Identification, Clinical and Cellular Data Integration.
Top alternatives and competitors to insitro include Cellarity, DeepLife, Manifold Bio, Alchemab Therapeutics Ltd, Paratus Sciences. These companies operate in related industries and serve comparable markets. You can compare them side by side on Bounce Watch.
insitro and Cellarity are both companies in similar industries. Compare their funding, team size, growth signals, and market position on Bounce Watch to see which one fits your needs.

Source: BounceWatch company record for insitro, https://bouncewatch.com/company/insitro, updated 21 September 2026. When citing, please name BounceWatch and link this page.

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