Manifold Bio logo — Organism-scale intelligence, designed in vivo

Manifold Bio

Organism-scale intelligence, designed in vivo

Founded 2020 United States Boston, United States 69 employees Series A Total: $60.40M Biotechnology, Health Care +2

General Information

Company Name Manifold Bio
Founded Year 2020
Location United States Boston, United States
Founders / Decision Makers
Team member
Employees 69
Industries Biotechnology, Health Care, Health and Wellness +1
Funding Stage Series A
Business Model B2B, Platform, API
Revenue Model Licensing, Performance Based, Service Fee
Social

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Recorded by Bounce Watch from public sources. Every entry below carries the date we observed it, and when we have not looked recently the page says so rather than leaving silence to imply nothing happened.

Feature Release Sep 22, 2026

Manifold Bio has launched mBER-2, the latest iteration of their scaled protein binder design platform.

New Partnership Sep 17, 2026

Manifold Bio announced it is an early partner in Anthropic's Life Sciences Verification Program, through which life science professionals can use Anthropic's models.

About Manifold Bio

Manifold Bio, founded in 2020, is a cutting-edge platform therapeutics company headquartered in the United States. The company is known for its bold tagline: "Organism-scale intelligence, designed in vivo". It specializes in leveraging biotechnology, healthcare, health and wellness, and pharmaceuticals to create impactful solutions in the pharmaceutical industry.

The company's distinctive approach is embodied in its mDesign engine, which uniquely integrates AI-guided protein design with multiplexed in vivo data generation. This process enables a continuous cycle of design and translation, ultimately aiming to build a 'virtual organism.' Manifold Bio not only advances its internal pipeline but also collaborates with major global pharmaceutical partners to ensure organism-scale biology has a profound clinical impact.

Recently, Manifold Bio secured a $15.00M Series A investment on April 1, 2024, with contributions from notable investors like SK Ventures, Calibrate Ventures, and TQ Ventures. This investment underscores the growing confidence in Manifold Bio's innovative platform and its potential to revolutionize therapeutic development.

Taxonomy: AI-guided therapeutics, in vivo discovery platform, protein design, multiplexed data generation, virtual organism development, therapeutics pipeline, pharmaceutical collaboration, organism-scale biology, protein barcoding, measurement-driven design, biotechnology innovation, multiplexed quantitation, drug development, platform therapeutics

Services & Products

AI-powered protein design
In vivo biologics validation
Multiplexed screening experiments
Therapeutic pipeline development
Partner collaborations

Target Customers

Biopharma companies Medical researchers Healthcare institutions Biotechnology partners Academic institutions

Funding Rounds & Investors (5)

View All
Funding Stage Amount Investors Lead Investors Date
Series A $15.00M 3
SK Ventures, Calibrate Ventures +1
01 Apr 2024
Series A $40.00M 7
Fifty Years, Horizon Ventures +5
01 Jul 2022
Seed $5.40M 4
Fifty Years, Playground Global +2
01 Sep 2020
Round Undisclosed -
01 Apr 2020
Spinout Undisclosed 2
Wyss Institute, Harvard University
01 May 2019

Manifold Bio Alternatives & Competitors

View All Alternatives
Manifold Bio vs
iktos
iktos France

Artificial intelligence for new drug design

Series A
85 employees
AI, Biotechnology
Manifold Bio vs
A-Alpha Bio
A-Alpha Bio United States

The protein-protein interaction company

Grant
50 employees
Biotechnology, Health Care
Manifold Bio vs
Antiverse
Antiverse United Kingdom

Designing functional antibodies for the most challenging targets.

Series A
33 employees
AI, Biotechnology

FAQ About Manifold Bio

Organism-scale intelligence, designed in vivo
Manifold Bio was founded in 2020.
Manifold Bio is headquartered in Boston, United States.
Manifold Bio operates in Biotechnology, Health Care, Health and Wellness and Pharmaceutical. Its work centres on AI-guided therapeutics, in vivo discovery platform, protein design and multiplexed data generation. Its customers include Biopharma companies, Medical researchers and Healthcare institutions.
Manifold Bio has a B2B, Platform and API business model. Its revenue comes from Licensing, Performance Based and Service Fee.
Manifold Bio has approximately 69 employees.
Manifold Bio has completed 5 funding rounds, raising a total of $60.40M. The latest funding stage is Series A.
Manifold Bio offers: AI-powered protein design, In vivo biologics validation, Multiplexed screening experiments, Therapeutic pipeline development, Partner collaborations.
Top alternatives and competitors to Manifold Bio include iktos, A-Alpha Bio, Antiverse, Gandeeva Therapeutics, Anavo Therapeutics BV. These companies operate in related industries and serve comparable markets. You can compare them side by side on Bounce Watch.
Manifold Bio and iktos are both companies in similar industries. Compare their funding, team size, growth signals, and market position on Bounce Watch to see which one fits your needs.

Source: BounceWatch company record for Manifold Bio, https://bouncewatch.com/company/manifold-bio, updated 30 June 2026. When citing, please name BounceWatch and link this page.

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