Replay logo — Reprogramming biology by writing and delivering big DNA

Replay

Reprogramming biology by writing and delivering big DNA

Founded 2021 United States San Diego, United States 30 employees Acquired Total: $56.56M Biotechnology, Health and Wellness

General Information

Company Name Replay
Founded Year 2021
Location United States San Diego, United States
Founders / Decision Makers
Team member
Employees 30
Industries Biotechnology, Health and Wellness
Funding Stage Acquired
Business Model B2B, Platform, B2B2B
Revenue Model Licensing, Service Fee
Social

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About Replay

Replay, founded in 2021 and headquartered in the United States, is carving a niche in the Biotechnology and Health and Wellness sectors. The company's slogan, "Reprogramming biology by writing and delivering big DNA," encapsulates its mission to redefine genomic medicine through innovative genome writing and high-capacity DNA delivery technologies.

Replay has built a comprehensive toolkit that includes a high payload capacity HSV platform, a hypoimmunogenic platform, and a genome writing platform. These technologies target and overcome scientific hurdles hampering clinical advancements in genomic medicine. Employing a hub-and-spoke business model, Replay develops core technologies while its product companies focus on therapeutic applications. Notably, the synHSV™ technology is harnessed to address diseases impacting the skin, eye, brain, and muscle. Additionally, an enzyme writing venture utilizes machine learning to enhance genomic functionality.

The company's recent $55.00M Series A investment on July 25, 2022, featured backers like Axial VC, Lansdowne Partners, and Kohlberg Kravis Roberts, underlining investor confidence in its groundbreaking potential. With leadership composed of distinguished academics and industry veterans, Replay is poised to advance the frontiers of genomic medicine.

Business keywords: genomic medicine, genome writing, big DNA delivery, HSV platform, hypoimmunogenic platform, gene therapy, therapeutic development, high payload capacity, synHSV technology, skin diseases, eye diseases, brain diseases, muscle diseases, enzyme writing, machine learning in genomics

Services & Products

Development of HSV vectors for gene therapy applications
Biomedical research and development

Target Customers

Healthcare Providers Biotech Companies Pharmaceutical Companies Research Institutions

Funding Rounds & Investors (5)

View All
Funding Stage Amount Investors Lead Investors Date
Acquisition Undisclosed 1
LEO pharma
01 Apr 2026
Grant $1.56M 1
Bill & Melinda Gates Foundation
01 Nov 2022
Seed $55.00M 7
ARTIS Ventures, KKR +5
01 Jul 2022
Seed Undisclosed -
01 Aug 2020
Spinout Undisclosed 1
University of Pittsburgh
01 Jan 2020

Replay Alternatives & Competitors

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Exegenesis Bio
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FAQ About Replay

Reprogramming biology by writing and delivering big DNA
Replay was founded in 2021.
Replay is headquartered in San Diego, United States.
Replay operates in Biotechnology and Health and Wellness. Its work centres on genomic medicine, genome writing, big DNA delivery and HSV platform. Its customers include Healthcare Providers, Biotech Companies and Pharmaceutical Companies.
Replay has a B2B, Platform and B2B2B business model. Its revenue comes from Licensing and Service Fee.
Replay has approximately 30 employees.
Replay has completed 5 funding rounds, raising a total of $56.56M. The latest funding stage is Acquired.
Replay offers: Development of HSV vectors for gene therapy applications, Biomedical research and development.
Top alternatives and competitors to Replay include Affinia Therapeutics, Mogrify, Exegenesis Bio, EmendoBio, Tessera Therapeutics. These companies operate in related industries and serve comparable markets. You can compare them side by side on Bounce Watch.
Replay and Affinia Therapeutics are both companies in similar industries. Compare their funding, team size, growth signals, and market position on Bounce Watch to see which one fits your needs.

Source: BounceWatch company record for Replay, https://bouncewatch.com/company/replay, updated 28 June 2026. When citing, please name BounceWatch and link this page.

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