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ROME Therapeutics logo — Harnessing the power of the repeatome to develop a new class...

ROME Therapeutics

Harnessing the power of the repeatome to develop a new class of therapies for cancer and autoimmune diseases.

Founded 2020 United States Boston, United States 16 employees Acquired Total: $199.00M Biotechnology, Health Care +1

General Information

Company Name ROME Therapeutics
Founded Year 2020
Location United States Boston, United States
Employees 16
Industries Biotechnology, Health Care, Pharmaceutical
Funding Stage Acquired
Business Model B2B, D2C
Revenue Model Licensing, Performance Based, Product Sales
Social

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About ROME Therapeutics

ROME Therapeutics, founded in 2020, is pioneering new paths in the biotech sector by targeting the repeatome, a vast, largely unexplored component of the genome. By focusing on this uncharted genetic material, often dismissed as "junk DNA," ROME is opening compelling avenues in the treatment of cancer and autoimmune diseases, offering the potential for revolutionary therapies in these fields.

Since its inception, ROME has identified multiple drug targets and initiated several discovery programs. The early involvement of premier investors like GV, in collaboration with ARCH Venture Partners and Partners Innovation Fund, underscores the startup's strong potential and industry validation. The headquarters in Cambridge, Mass., positions ROME advantageously within a vibrant biotech ecosystem.

Significant recent backing includes an acquisition investment by Pretzel in early 2026, signifying confidence in ROME's strategic direction and the promising application of its scientific discoveries in healthcare.

Business keywords: repeatome, junk DNA, cancer therapies, autoimmune disease therapies, drug discovery, genetic material exploration, oncology, immunology, virology, machine learning in biology, biotechnology innovation, therapeutic development, biological research, genomic research

Services & Products

Developing novel therapies targeting the dark genome
Inhibition of LINE-1 reverse transcriptase

Target Customers

Patients with cancer Patients with autoimmune diseases Patients with neurodegenerative diseases Healthcare providers Biopharmaceutical partners

Funding Rounds & Investors (4)

View All
Funding Stage Amount Investors Lead Investors Date
Acquisition Undisclosed 1
Pretzel
01 Jan 2026
Series B $72.00M 15
Arch Venture Partners, Casdin Capital +13
01 Sep 2023
Series B $77.00M 7
Arch Venture Partners, Casdin Capital +5
01 Sep 2021
Series A $50.00M 3
Arch Venture Partners, GV +1
01 Apr 2020

ROME Therapeutics Alternatives & Competitors

View All Alternatives
ROME Therapeutics vs
Mestag Therapeutics
Mestag Therapeutics United Kingdom

New therapies for inflammatory disease and cancer by targeting fibroblast immunology

Seed
40 employees
Biotechnology, Health Care
ROME Therapeutics vs
Adendra Therapeutics
Adendra Therapeutics United Kingdom

Translating dendritic cell biology into new therapies for cancer and autoimmunity.

Series A
3 employees
Biopharma, Biotechnology
ROME Therapeutics vs
Georgiamune Inc.
Georgiamune Inc. United States

Georgiamune is reprogramming immune signaling pathways to redirect the immune system to fight diseas...

Series A
30 employees
Biotechnology, Health Care

FAQ About ROME Therapeutics

Harnessing the power of the repeatome to develop a new class of therapies for cancer and autoimmune diseases.
ROME Therapeutics was founded in 2020.
ROME Therapeutics is headquartered in Boston, United States.
ROME Therapeutics operates in Biotechnology, Health Care and Pharmaceutical. Its work centres on repeatome, junk DNA, cancer therapies and autoimmune disease therapies. Its customers include Patients with cancer, Patients with autoimmune diseases and Patients with neurodegenerative diseases.
ROME Therapeutics has a B2B and D2C business model. Its revenue comes from Licensing, Performance Based and Product Sales.
ROME Therapeutics has approximately 16 employees.
ROME Therapeutics has completed 4 funding rounds, raising a total of $199.00M. The latest funding stage is Acquired.
ROME Therapeutics offers: Developing novel therapies targeting the dark genome, Inhibition of LINE-1 reverse transcriptase.
Top alternatives and competitors to ROME Therapeutics include Mestag Therapeutics, Adendra Therapeutics, Georgiamune Inc., Paratus Sciences, Avenzo Therapeutics. These companies operate in related industries and serve comparable markets. You can compare them side by side on Bounce Watch.
ROME Therapeutics and Mestag Therapeutics are both companies in similar industries. Compare their funding, team size, growth signals, and market position on Bounce Watch to see which one fits your needs.

Source: BounceWatch company record for ROME Therapeutics, https://bouncewatch.com/company/rome-therapeutics, updated 12 April 2026. When citing, please name BounceWatch and link this page.

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