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Cara Therapeutics logo — Transforming the way pruritus is treated to bring quality to...

Cara Therapeutics

Transforming the way pruritus is treated to bring quality to the lives of those who suffer

Founded 2004 United States Stamford, United States 46 employees Post-IPO Debt Total: $517.20M Biotechnology, Health Care +1

General Information

Company Name Cara Therapeutics
Founded Year 2004
Location United States Stamford, United States
Employees 46
Industries Biotechnology, Health Care, Health and Wellness
Funding Stage Post-IPO Debt
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About Cara Therapeutics

Cara Therapeutics, founded in 2004 and headquartered in the United States, is a biopharmaceutical innovator committed to enhancing the treatment of pruritus through novel therapeutic approaches. With its slogan, "Transforming the way pruritus is treated to bring quality to the lives of those who suffer," the company is making significant strides in addressing this chronic condition.

At the forefront of its development pipeline is the oral formulation of difelikefalin, which targets kappa opioid receptors to alleviate pruritus, particularly for patients with notalgia paresthetica, an often-overlooked neuropathy. Currently in a Phase 2/3 clinical trial, results are anticipated in Q3 2024. Meanwhile, their IV formulation is widely recognized, with approvals across the U.S., EU, and beyond. This version is already enhancing lives of those with chronic kidney disease undergoing hemodialysis.

In November 2023, Cara Therapeutics secured a $40.00M post-IPO debt investment from HealthCare Royalty Partners, reinforcing its financial stability and capacity to advance its groundbreaking therapeutic initiatives.

Business keywords: biopharmaceutical company, pruritus treatment, KORSUVA, difelikefalin, FDA-approved treatment, chronic kidney disease, hemodialysis, oral formulation, Phase 3 programs, non-dialysis dependent advanced chronic kidney disease, atopic dermatitis, notalgia paresthetica, clinical trials, innovation, medical research

Funding Rounds & Investors (10)

View All
Funding Stage Amount Investors Lead Investors Date
Post IPO Debt $40.00M 1
HealthCare Royalty Partners
02 Nov 2023
Post IPO Equity $145.50M -
24 Jul 2019
Post IPO Equity $98.30M -
17 Jul 2018
Post IPO Equity $92.10M -
29 Mar 2017
Post IPO Equity $80.50M -
27 Jul 2015
Series D $4.80M 7
Alta Partners, Rho Ventures +5
21 May 2012
Series D $15.00M 8
Connecticut Innovations, Alta Partners +6
21 Jul 2010
Series C $12.30M 4
Connecticut Innovations, Ascent Biomedical Ventures +2
25 Jul 2008
Series C $24.00M 5
Mitsubishi UFJ Capital, Alta Partners +3
28 Nov 2006
Series B $4.70M 2
Ascent Biomedical Ventures, Esperante Ventures
21 Dec 2005

Cara Therapeutics Alternatives & Competitors

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FAQ About Cara Therapeutics

Transforming the way pruritus is treated to bring quality to the lives of those who suffer
Cara Therapeutics was founded in 2004.
Cara Therapeutics is headquartered in Stamford, United States.
Cara Therapeutics operates in Biotechnology, Health Care and Health and Wellness. Its work centres on biopharmaceutical company, pruritus treatment, KORSUVA and difelikefalin.
Cara Therapeutics has approximately 46 employees.
Cara Therapeutics has completed 10 funding rounds, raising a total of $517.20M. The latest funding stage is Post-IPO Debt.
Top alternatives and competitors to Cara Therapeutics include Affymax, ASLAN Pharmaceuticals, Allena Pharmaceuticals, Inc., ProKidney Corp., Gallant. These companies operate in related industries and serve comparable markets. You can compare them side by side on Bounce Watch.
Cara Therapeutics and Affymax are both companies in similar industries. Compare their funding, team size, growth signals, and market position on Bounce Watch to see which one fits your needs.

Source: BounceWatch company record for Cara Therapeutics, https://bouncewatch.com/company/cara-therapeutics, updated 24 October 2025. When citing, please name BounceWatch and link this page.

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